Genome wide interaction study of pathogenic protein in Alzheimer's disease Lead Investigator: Hang-Rai Kim Institution : Korea Advanced Institute of Science and Technology E-Mail : alwaysolleh26@gmail.com Proposal ID : 1185 Proposal Description: 1) To identify common genetic variant (SNP) that interacts with pathogenic proteins (tau and beta-amyloid) in Alzheimer's disease. 2) To evaluate the effect of identified SNP on the individual's prognosis using longitudinal data provided by NACC 3) Identifying such SNP would help us understanding patho-mechanism of Alzheimer's disease and provide evidences for personalized medicine in neurodegenerative disease.